The First Cystine Stone?

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Stone clustering of patients with cystine urinary stone formation.

OBJECTIVES To explore the history of symptomatic cystine stone formation. Cystinuria is a genetic defect that may result in the formation of recurrent cystine calculi. METHODS Thirty-four patients with cystinuria were retrospectively evaluated for treatment patterns, medical prophylaxis, and renal outcome. Patients were offered a conservative surgical regimen and routine radiographic and labo...

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Treating the cystine stone former presents a singular clinical challenge

Transl Androl Urol 2014;3(3):234 www.amepc.org/tau Cystinuria represents a relatively rare hereditary condition leading to impairment of the renal proximal tubule’s dibasic amino acid transporter. The only manifestation of this disease is calculi formation. Unlike other nephrolithiasis disease processes, cystine stone formation is due directly to supersaturation of an insoluble solute precipita...

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The challenge of cystine and struvite stone formers: clinical, metabolic and surgical assessment

PURPOSE To compare the clinical, metabolic, and calculi characteristics of cystine and struvite stone patients after percutaneous nephrolithotripsy (PCNL). MATERIAL AND METHODS Between January/2006-July/2013, 11 cystine stone patients were treated in our clinic. Of those, 3 were excluded due to incomplete follow-up. Eight cystine stone patients (2 with bilateral disease; 10 renal units-RU) we...

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Garner Trouble: Reading The First Stone as a Detective Narrative

Helen Garner’s The First Stone (1995) has commonly been read as a feministauthored attack on feminism. I concur with this reading, but also argue that this text contains some distinctly ‘queer’ aspects that have previously been overlooked by critics. I suggest that a useful way of emphasising and exploring these aspects is by reading The First Stone as a detective narrative. I contend that Garn...

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Cystine Stones

Cystine stones occur in subjects carrying two autosomal mutant alleles resulting in excessive excretion of cystine, ornithine, arginine and lysine – hence the condition cystinuria. About 1:15–25 000 NSW neonates have been found to have cystinuria, with a gene frequency in Australia calculated to be about 1:4000 individuals. Since these studies were published, the mutant alleles have been identi...

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ژورنال

عنوان ژورنال: BMJ

سال: 1964

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.5374.53